Dwi Hudiyanti
Research Areas
Physical Chemistry, Materials, Natural Product and Colloid Chemistry
Research focuses on:
- Studies on phospholipid self-assembly and liposome formation
- Molecular dynamics simulations to understand membrane structure and stability
- Development of liposome-based drug delivery systems for vitamin C, curcumin, and other bioactive compounds
- Investigation of molecular interactions in colloidal systems such as emulsions and membranes
- Applications in pharmaceutical drug delivery, food systems (such as coconut milk emulsions), and biomolecule-based materials
Education
Undergraduate
Universitas Gadjah Mada, 1983-1988
Pengaruh Amilum, Gliserol, Tulang Ayam, Gelatin, Variasi pH, Dan Variasi Pengadukan Terhadap Laju Kriming Santan Kelapa Dan Susu
Supervisor: Drs. Jaka Sasmita and Drs. Iip Izul Falah
Master
University of Bristol, 1992-1995
A Study of Coconut Milk
Supervisor: Dr. Jim Goodwin
Doctor
Universitas Gadjah Mada, 2006-2013
Pembuatan Dan Karakterisasi Liposom Dari Fosfolipida Kelapa (Cocos Nucifera), Kemiri (Aleurites Moluccana Willd) Dan Wijen (Sesamum Indicum L. Syn.)
Supervisor: Prof. Dr. Sri Noegrohati, Apt., Prof. Dr. Narsito and Tri Joko Raharjo, S.Si, M.Si., Ph.D
Research Project
| No | Research Projects | Year | Budget (Rp.) | Source of Funds |
| 1 | Eksplorasi Liposom Alam Sebagai CoEnkapsulan Berbagai Bahan Bioaktif Berpotensi Imun Booster Pada Pencegahan Infeksi Virus (1st Year) | 2021 | 194.200.000 | Kemenristek Dikti PDUPT |
| 2 | Pengembangan Formula Liposomal Dari Kombinasi Ekstrak Kulit Manggis (Garsinia mangostana) -Pegagan (Centella asiatica) Sebagai Obat Herbal Antiinfeksi (3rd Year) | 2021 | 400.000.000 | Kemenristek Dikti KRUPT |
| 3 | Isolasi dan Karakterisasi Fosfolipid Kelapa Spesi Kolin menggunakan Kromatografi Cair Vakum (KCV) | 2021 | 10.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 4 | Curcumin Loaded Liposom Alam Untuk Terapi Anticancer (3rd Year) | 2021 | 168.000.000 | Kemenristek Dikti PDUPT |
| 5 | Pengembangan Formula Liposomal Dari Kombinasi Ekstrak Kulit Manggis (Garsinia mangostana) -Pegagan (Centella asiatica) sebagai Obat Herbal Antiinfeksi (2nd Year) | 2020 | 400.000.000 | Kemenristek Dikti KRUPT |
| 6 | Isolasi dan Karakterisasi Fosfolipid Kelapa Spesi Kolin menggunakan Kromatografi Cair Vakum (KCV) | 2020 | 10.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 7 | Curcumin Loaded Liposom Alam Untuk Terapi Anticancer (2nd Year) | 2020 | 147.323.400 | Kemenristek Dikti PDUPT |
| 8 | Pengembangan Formula Liposomal Dari Kombinasi Ekstrak Kulit Manggis (Garsinia mangostana) -Pegagan (Centella asiatica) Sebagai Obat Herbal Antiinfeksi (1st Year) | 2019 | 435.899.000 | Kemenristek Dikti KRUPT |
| 9 | Studi Tentang Enkapsulasi Α-Tokoferol dalam Gom Arab | 2019 | 20.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 10 | Curcumin Loaded Liposom Alam Untuk Terapi Anticancer (1st Year) | 2019 | 154.675.000 | Kemenristek Dikti PDUPT |
| 11 | Enkapsulasi Vitamin C Dalam Liposom Dari Fosfolipid Kepala Spesies Etanolamin | 2018 | 20.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 12 | Liposom Dari Fosfolipida Alam Sebagai Nanocarrier Bahan Aktif Ferro Sulfat, Vitamin C Dan Vitamin A Untuk Aplikasi Medis (2nd Year) | 2018 | 310.000.000 | Kemenristek Dikti PDUPT |
| 13 | Enkapsulasi Bahan Aktif Dalam Liposom Dari Fosfolipid Kepala Spesies Kolin | 2017 | 20.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 14 | Liposom Dari Fosfolipida Alam Sebagai Nanocarrier Bahan Aktif Ferro Sulfat, Vitamin C Dan Vitamin A Untuk Aplikasi Medis (1st Year) | 2017 | 275.000.000 | Kemenristek Dikti PTUPT |
| 15 | Pengembangan Bahan Alam dan Bioorganik Berbasisi Pada Pemanfaatan Potensi Lokal, Bagian IV (2016): Peningkatan Daya Guna Tanaman Lengkuas (Alpina purpurata) | 2016 | 30.000.000 | PNBP Departemen Kimia FSM UNDIP |
| 16 | Pengembangan Sediaan Anti Kanker Liposomal Hiptolida Dari Berbagai Fosfolipida Alam (2nd Year) | 2016 | 150.000.000 | Kemenristek Dikti PUPT |
| 17 | Pengembangan Sediaan Anti Kanker Liposomal Hiptolida Dari Berbagai Fosfolipida Alam | 2015 | 107.500.000 | Kemenristek Dikti PUPT |
| 18 | Pengembangan Bahan Alam dan Bioorganik Berbasisi Pada Pemanfaatan Potensi Lokal, Bagian III (2015): Peningkatan Daya Guna Tanaman Lengkuas (Alpina purpurata) | 2015 | 30.000.000 | PNBP Jurusan Kimia FSM UNDIP |
| 19 | Dinamika Agregasi Spesies Molekul DilaurilFosfolipida Dalam Medium Akuos (2nd Year) | 2015 | 65.000.000 | PNBP UNDIP |
| 20 | Pengembangan Bahan Alam dan Bioorganik Berbasisi Pada Pemanfaatan Potensi Lokal, Bagian II (2014): Peningkatan Daya Guna Tanaman Lengkuas (Alpina purpurata) | 2014 | 30.000.000 | PNBP Jurusan Kimia FSM UNDIP |
| 21 | Dinamika Agregasi Spesies Molekul DilaurilFosfolipida Dalam Medium Akuos | 2014 | 60.000.000 | PNBP UNDIP |
| 22 | Enkapsulasi Karotenoid Dalam Nanokapsul Berbahan Dasar Fosfolipida Kelapa (2nd Year) | 2012 | 45.000.000 | DP2M Hibah bersaing |
| 23 | Enkapsulasi Karotenoid Dalam Nanokapsul Berbahan Dasar Fosfolipida Kelapa | 2011 | 45.000.000 | DP2M Hibah bersaing |
Publications
| 1 | Investigation On The Morphology and Properties Of Aggregate Structures Of Natural Phospholipids In Aqueous System Using Cryo-Tem
Hudiyanti, D., Raharjo, T.J., Narsito,, Noegrohati, S Indonesian Journal of Chemistry (IJC) Vol. 12 (1) 2012 http://pdm-mipa.ugm.ac.id/ojs/index.php/ijc/ article/viewArticle/672 |
| 2 | Isolasi Dan Karakterisasi Lesitin Kelapa dan Wijen
Hudiyanti, D., Raharjo, T.J., Narsito,, Noegrohati, S Jurnal Agritech Vol. 32 (1) 2012 |
| 3 | Organo-Silica Membrane Prepared from TEOS-TEVS Modified with Organic-Acid Catalyst for Brackish Water Desalination
D Hudiyanti, A Supardi, S Nugroho Jurnal Sains dan Matematika Vol 20 (4) 2012 http://www.ejournal.undip.ac.id/index.php/sm/article/view/8020 |
| 4 | A Coarse-Grained Molecular Dynamics Simulation Using NAMD Package to Reveal Aggregation Profile of Phospholipids Self-Assembly in WaterHudiyanti, D., Radifar, M., Raharjo, T.J., Narsito, N., Noegrohati, SJ Chem. 4. 2014http://www.hindawi.com/journals/jchem/2014/273084/ |
| 5 | Study on Leakage of Sesame (Sesamum indicum L.) and Coconut (Cocos nucifera L.) Liposomes
Hudiyanti, D., Raharjo, T.J., Narsito, N., Noegrohati, S Orient. J. Chem. Vol 31 (1) 435-439, 2015 |
| 6 | Chemical composition and Phospholipids Content of Indonesian Jack Bean (Canavalia ensiformis L.)
Hudiyanti, D., Arya, A.P., Siahaan, P., Suyati, L. Orient. J. Chem. Vol. 31(4), 2043-2046 (2015) http://dx.doi.org/10.13005/ojc/310423 |
| 7 | Studi Pendahuluan Tentang Enkapsulasi Vitamin C dalam Liposom Kelapa (Cocos nucifera L.)
Dwi Hudiyanti, Desita Triana, Parsaoran Siahaan Jurnal Kimia Sains dan Aplikasi (JKSA) Vol. 20 (1), 5 – 8 (2017) |
| 8 | The Optimum Conditions of Carboxymethyl Chitosan Synthesis on Drug Delivery Application and Its Release of Kinetics Study
Siahaan P.,Mentari N.C.,Wiedyanto U.O.,Hudiyanti D.,Hildayani S.Z.,Laksitorini M.D. Indonesian Journal of Chemistry (IJC) Vol. 17 (2), 291-300 (2017) |
| 9 | Molecular Docking of Interaction between E-Cadherin Protein and Conformational Structure of Cyclic Peptide ADTC3 (Ac-CADTPC-NH2) Simulated on 20 ns
A Manna, MD Laksitorini, D Hudiyanti, P Siahaan Jurnal Kimia Sains dan Aplikasi (JKSA) Vol. 20 (1), 30-36 (2017) |
| 10 | Simultant encapsulation of vitamin C and beta-carotene in sesame (Sesamum indicum l.) liposomes
Hudiyanti, D., Fawrin, H., Siahaan, P. IOP Conference Series: Materials Science and Engineering 349(1),012014 (2018) http://iopscience.iop.org/article/10.1088/1757-899X/349/1/012014 |
| 11 | Coconut (Cocos nucifera L.) Lipids: Extraction and Characterization
Hudiyanti, D., Al Khafiz, M.F., Anam, K. Oriental Journal Of Chemistry Vol. 34 / 2 pp: 1136 s/d 1140 (2018) |
| 12 | Probing the Interaction between Cyclic ADTC1 Ac- CADTPPVC-NH2) Peptide with EC1-EC2 domain of Ecadherin using Molecular Docking Approach
Siahaan, P., Wuning, S., Manna, A., Prasasty, V.D., Hudiyanti, D IOP Conf. Series: Materials Science and Engineering 349(1), 012050 (2018) https://iopscience.iop.org/article/10.1088/1757-899X/349/1/012050 |
| 13 | Ab initio computational study of -N-C and -O-C bonding formation: functional group modification reaction based chitosan
Siahaan P.,Salimah S.N.M.,Sipangkar M.J.,Hudiyanti D.,Djunaidi M.C.,Laksitorini M.D IOP Conf. Series: Materials Science and Engineering 349(1), 012049 (2018) |
| 14 | A Study of Coconut (Cocos Nucifera L.) Phosphatidylcholine Species
D Hudiyanti, M Jayanti, MF Al- Khafiz, K Anam Oriental Journal Of Chemistry Vol. 34 (6) pp: 2963 s/d 2968 (2018) |
| 15 | Probing of interaction mode between linier and cyclic ADTC6 (Ac-CDTPPCNH2) with E-cadherin protein using molecular docking approach
Siahaan, P., Kaswanda, J.A., Budiyanto, R., Hudiyanti, D., Prasasty, V.D. IOP Conference Series: Materials Science and Engineering 509(1),012108 (2019) |
| 16 | Cholesterol implications on coconut liposomes encapsulation of beta-carotene and vitamin C
Hudiyanti, D., Aminah, S., Hikmahwati, Y., Siahaan, P IOP Conference Series: Materials Science and Engineering 509(1),012108 (2019) |
| 17 | Encapsulation of Vitamin C in Sesame Liposomes: Computational and Experimental Studies
Hudiyanti, D., Hamidi, N.I., Anugrah, D.S.B., Salimah, S.N.M., Siahaan, P Open Chemistry Vol. 17 (1) 24 August 2019, Pages 537-543 |
| 18 | Ab initio computational study of electronic structure of-o-c bonding formation on chitosan polymer-part 1: Effects of NaOH
Yuliani, S.V., Salimah, S.N.M., Hudiyanti, D., Laksitorini, M.D., Siahaan, P Journal of Physics: Conference Series, 2019, 1217(1), 12054 |
| 19 | Coconut Phospholipid Species: Isolation, Characterization and Application as Drug Delivery System in Research Advances on Coconut
Dwi Hudiyanti Nur Kamila Febriani kusuma Wardani Khairul Anam Book chapter: ISBN: 978-1-78985-210-3 IntechOpen, London UK |
| 20 | Key conditions of alpha- tocopherol encapsulation in gum Arabic dispersions
Al Khafiz, M.F., Hikmahwati, Y., Anam, K., Hudiyanti, D International Journal of Research in Pharmaceutical Sciences, 2019, 10(4), pp. 2622–2627 |
| 21 | Encapsulation of cinnamic acid and galangal extracts in coconut (Cocos nucifera L.) liposomes
Hudiyanti, D., Al-Khafiz, M.F., Anam, K. Journal of Physics: Conference Series, 2020, 1442(1), 012056 |
| 22 | Intermolecular hydrogen bond interactions in N – carboxymethyl chitosan and n H2O: DFT and NBO studies
Safitri, B., Hudiyanti, D., Laksitorini, M.D.,Sasongko, N.A., Siahaan, P AIP Conference Proceedings, 2020, 2237, 020081 |
| 23 | Liposomes from jack beans phospholipid extract for delivering vitamin C
Hudiyanti, D., Sari, R.I., Arya, A.P.,Siahaan, P AIP Conference Proceedings, 2020, 2237, 020064 |
| 24 | Probing the interaction between EC1-EC2 domain of E-cadherin with conformational structure of cyclic ADTC7 (Ac-CDTPDC- NH2) peptide using molecular docking approach
Siahaan P, Darmastuti N.E,,Aisyafalah S., Sasongko N.A, Hudiyanti D., Asy’ari M., Prasasty V.D. Journal of Physics: Conference Series, 2020, 1524(1), 012081 |
| 25 | A review of polysaccharide-zinc oxide nanocomposites as safe coating for fruits preservation
Anugrah D.S.B, Alexander H., Pramitasari R., Hudiyanti D., Sagita C.P Coatings, 2020, 10(10), pp. 1–15, 988 |
| 26 | Assessing encapsulation of curcumin in cocoliposome: In vitro study
Hudiyanti, D., Al Khafiz, M.F., Anam, K., Siahaan, P., Suyati, L. Open Chemistry, 2021, 19(1), pp. 358–366 |
Scientific meeting
| No | Scientific Meeting | Time and Place |
| 1 | Seminar Nasional Kimia & Pendidikan Kimia Kerjasama Jurusan Kimia UNS-UNDIP-UNNES | Surakarta, Indonesia, 22 November 2008 |
| 2 | Seminar Nasional Kimia & Pendidikan Kimia Kerjasama Jurusan Kimia UNS-UNDIP-UNNES | Surakarta, Indonesia, 22 November 2008 |
| 3 | Bandung International Conference on Medicinal Chemistry | Bandung, Indonesia, August 6-8, 2009 |
| 4 | International Conference for Young Chemists | Penang, Malaysia, June 23rd-25th 2010 |
| 5 | Seminar Nasional Kimia II HKI Jateng | Semarang, Indonesia, 24 Juli 2010 |
| 6 | The 2nd International Conference on Chemical Science | Bandung, Indonesia, November 26-27, 2010 |
| 7 | International Seminar on Cosmetics | Surakarta, Indonesia, September 7 to 8, 2015 |
| 8 | Seminar Ilmiah Nasional Kimia Jurusan Kimia Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Jenderal Achmad Yani | Bandung, Indonesia, 8 Oktober 2011 |
| 9 | 2nd International Seminar on New Paradigm and Innovation on Natural Sciences and its Applications | Semarang, Indonesia, October 4th 2012, |
| 10 | Seminar Nasional Kimia Terapan Indonesia 2013 | Solo, Indonesia, 23 Mei 2013 |
| 11 | The 9th Joint Conference on Chemistry, organized by the Diponegoro Unversity | Semarang, Indonesia, 12-13 November 2014 |
| 12 | The 5th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application (5th ISNPINSA Programme) | Semarang, 7-8 October 2015 |
| 13 | The 10th Joint Conference on Chemistry, organized by the Sebelas Maret Unversity | Solo, 8th -11th September 2015 |
| 14 | The 11th Joint Conference on Chemistry, organized by the Universitas Jendral Soedirman | Purwokerto, Indonesia, 15th -16th September, 2016 |
| 15 | 6th International Seminar on New Paradigm and Innovation on Natural Sciences and Its Application (6th ISNPINSA Programme) | Semarang, Indonesia 5-6 Oktober 2016 |
| 16 | The 12th Joint Conference on Chemistry, organized by the Universitas Negeri Semarang | Semarang, Indonesia, 19th -20th September, 2017 |
| 17 | Basic and Applied Sciences Interdisciplinary Conference 2017 (BASIC 2017) | Jakarta, Indonesia 18-19th August 2017 |
| 18 | The 13th Joint Conference on Chemistry, organized by the Diponegoro University Semarang | Semarang, Indonesia 7-8th September 2018 |
| 19 | The 7th International Conference on Chemistry, organized by the Cendrawasih University, Jayapura | Jayapura, Indonesia 26-27th September 2018 |
| 20 | The 14th Joint Conference on Chemistry, organized by Universitas Sebelas Maret Surakarta | Surakarta, Indonesia 10-11th September 2019 |
| 21 | The 8th International Conference on Chemistry, organized by IPB University, Bogor | Bogor, Indonesia 6-7th August 2019 |
| 22 | The 14th Joint Conference on Chemistry, organized UKSW Salatiga | Salatiga, Indonesia Indonesia, 9th September 2020 |
| 23 | Natural resources as potential agents for Covid- 19 prevention UMT-INDONESIA UNIVERSITIES Joint Webinar on Science organized by IMB-UMT Malaysia | Indonsia, 20th October 2020 |
Community Service
| No | Year | Community Service Activities |
| 1 | 2014 | Pengembangan Kompetensi Pembelajaran Ilmu Kimia pada Guru SMA Se-Jawa tengah melalui Komputer, Simulasi dan Animasi, tgl 26 Juni 2014 |
| 2 | 2014 | Anggota Pengabdian Masyarakat Jurusan Kimia dengan judul “Pelatihan Pembuatan Hand Sanitizer Alami” |
| 3 | 2014 | Anggota Pengabdian Masyarakat Jurusan Kimia dengan judul “Pelatihan Pembuatan SausTomat bagi Ibu-Ibu PKK Puri Asri Perdana RT 02 RW 16 Banyumanik Semarang” |
| 4 | 2015 | Penguatan Kompetensi Guru SMK se Jawa Tengah melalui Pelatihan Penulisan Karya Ilmiah yang Berkualitas, tgl 4 Juni 2015 |
| 5 | 2015 | Pengabdian Masyarakat Jurusan Kimia dengan judul “Pelatihan Pembuatan Sabun Cuci Piring” |
| 6 | 2015 | Pengabdian Masyarakat Jurusan Kimia dengan judul “Pelatihan Pembuatan Mi labu kuning bagi Ibu-Ibu PKK RT 02 RW 02 Bulusan Tembalang Semarang” |
| 7 | 2016 | Pelatihan Wirausaha Muda Pondok Pesantren Al-Mabrur Boja, Kendal |
| 8 | 2016 | Pengabdian Masyarakat Penerapan Program Komputasi Kimia Berbasis Windows dan Linux dalam Rangka Peningkatan Kualitas Pembelajaran dan Penguasaan Mater Kimia Para Guru Kimia SMA se-Jawa Tengah |
| 9 | 2016 | Pengabdian Masyarakat Pelatihan Metode Destilasi Uap Minyak Atsiri Kulit Jeruk untuk Siswa SMK Astra Mitra di Purwodadi |
| 10 | 2017 | Peningkatan Kualitas Mahasiswa Kimia Se-Kodya Semarang Melalui Penerapan Program Kimia Komputasi Berbasis Windows Dan Linux |
| 11 | 2017 | Pembuatan minuman jahe instan sebagai alternatif upaya pemberdayaan masyarakat di PKK bukit kencana jaya Meteseh |
| 12 | 2017 | Pelatihan Pembuatan Minuman Sehat Jahe Aren Instan |
| 13 | 2017 | Peningkatan penguasaan ilmu kimia bagi mahasiswa kimia UKSW melalui pelatihan kimia komputasi berbasis linux |
| 14 | 2017 | Pelatihan Pembuatan Mie Sehat Berprotein Tinggi |
| 15 | 2018 | Pembuatan Wedang Uwuh Minuman Sampah Yang Kaya Khasiat |
| 16 | 2018 | Pelatihan Pembuatan Bawang Hitam |
| 17 | 2018 | Pelatihan Pembuatan Nugget Tempe |
| 18 | 2018 | Pelatihan Pembuatan Mie Pelangi Berbahan Alami |
| 19 | 2018 | Peningkatan Penguasaan Ilmu Kimia Bagi Mahasiswa Kimia UKSW Melalui Pelatihan Kimia Komputasi Berbasis Linux : Pengaruh Tingkat Teori Dan Basis Set Pada Keakuratan Hasil Perhitungan Komputasi |
| 20 | 2018 | Pelatihan Komputasi Kimia Bagi Mahasiswa Kimia Se-Jawa Tengah Dan Daerah Istimewa Yogyakarta (Jateng dan DIY) ” Branch Out Chemistry With Computation” |
| 21 | 2018 | Pelatihan Pembuatan Aromaterapi untuk mendukung Kesehatan Keluarga |
| 22 | 2019 | Pelatihan Pembuatan Sabun Cuci Piring Berbahan Herbal |
| 23 | 2020 | Pelatihan pembuatan hand sanitizer untuk menghambat penyebaran virus corona |
| 24 | 2020 | Pelatihan Pembuatan Aromaterapi Untuk Penyegar Ruangan Rumah Sehat |
Awards
Dosen Teladan III FMIPA UNDIP (1996)
Tanda Kehormatan Satyalancana Karya Satya 10 Tahun Republik Indonesia (2001)
Tanda Kehormatan Satyalancana Karya Satya 20 Tahun Republik Indonesia (2012)
Penulis Artikel Pada Jurnal Bereputasi (2016)
Professional organization
1998-Present, HKI (Indonesia Chemical Society)